3-mmc / 3mmc / buy 3-mmc online

$150.00$3,050.00

CAS Number
1246816-62-5 ☒
ChemSpider
34445939
UNII
73Q9QTO1N4
Chemical and physical data
Formula C11H15NO
Molar mass 177.247 g·mol−1
3D model (JSmol)
Interactive image
Melting point 193.2 °C (379.8 °F) ± 0.2°C (hydrochloride salt)
Boiling point 280.5 °C (536.9 °F) ± 23.0°C at 760 mm Hg
Solubility in water 3-MMC is sparingly soluble in PBS; slightly soluble in ethanol, dimethyl sulfoxide, and dimethyl formamide.[1] mg/mL (20 °C)

Clear
N/A

Description

3-mmc / 3mmc / buy 3-mmc online

3-mmc / 3mmc / buy 3-mmc online . 3-Methylmethcathinone, also known as 3-MMC and metaphedrone,[2] is a designer drug from the substituted cathinone family. 3-MMC is closely related in structure to the more common illicit drug mephedrone (4-MMC), and is illegal in most countries that have banned mephedrone as it is a structural isomer of it. However, 3-MMC has still appeared on the recreational drug market as an alternative to mephedrone, and was first identified being sold in Sweden in 2012.[3] Unlike other legal highs 3-MMC was tested and characterized in large mammals,[4] providing much more knowledge about it than is known about other synthetic cathinones. 3-MMC is a monoamine transporter substrate that potently inhibits norepinephrine uptake and displays more pronounced dopaminergic vs. serotonergic activity

History
3-mmc / 3mmc / buy 3-mmc online was first encountered in Sweden in 2012,[6] it was created as a designer drug following the control in many countries of the related compound mephedrone. It was sold as a research chemical, usually in powder form. There is no known or reported medical use of 3-MMC and it is being used for recreation. Some fatal intoxications have been reported although only a few involved 3-MMC only.

Structure
3-Methylmethcathinone (3-mmc / 3mmc / buy 3-mmc online) chemical name is 2-(methylamino)-1-(3-methylphenyl)propan-1-one) and is a cathinone derivative, which is a synthetic form of phenylethylamines. 3-MMC has a cathinone which is substituted with a methyl group at the 3 position which makes it a structural isomer of Mephedrone.

3-mmc / 3mmc / buy 3-mmc online contains a chiral center at the C-2 carbon. Therefore two enantionmers exist, the R and S enantiomer. It is assumed that the S form is more potent due to its similarity to cathinone. But further research has to be done to confirm this.[8]

Synthesis
There are several ways to synthesize 3-MMC. One of ways to synthesize 3-mmc / 3mmc / buy 3-mmc online, which is adapted from Power et al, is to add ethyl magnesium bromide to 3-methylbenzaldehyde. The product is then oxidized by pyridinium chlorochromate on silica gel and brominated with hydrobromic acid to yield the bromo ketone. This bromo ketone is reacted with ethanolic methylamine to produce the 3-MMC free base, which can be converted to the hydrochloride salt by addition of ethereal hydrogen chloride.

Reactions
There are no simple conversions into controlled substances.

Available forms
The most common form of 3-MMC is as a white crystalline powder or as white solid crystals. Sometimes however it is also sold as capsules filled with 3-mmc / 3mmc / buy 3-mmc online. There is no information available whether it is a racemate or enantiomerically pure.

Mechanism of action
The studies of pharmacology are currently lacking but it was found 3-MMC just like 4-MMC inhibits norepinephrine(NET), serotonin(SERT) and dopamine(DAT) transporters. 3-MMC inhibits SERT and NET and more potently than the DAT which suggests that 3-MMC has stronger amphetamine-like stimulant properties compared to mephedrone.

3-MMC strongly binds to serotonin 5-HT1A, 5-HT2A and 5-HT2C receptors. In addition, 3-mmc / 3mmc / buy 3-mmc online binds weakly to the α1A and α2A adrenergic receptors.

Metabolism
The metabolism pathway of 3-mmc / 3mmc / buy 3-mmc onlineis not yet fully known. From analysis of human pubic hair of a drug dealer it is known that 3-methylephedrine and 3-methylnorephedrine are metabolites of the drug. A possible metabolic pathway is β-keto-reduction followed by N-demethylation.

Efficacy
Generally, 3-MMC is taken via inhalation, injection, insufflation or oral administration. Repeated use of 3-MMC in a single session, often via different routes, has also been seen. The dosages range from threshold, light, common, strong and heavy corresponding to 50mg, 50-150mg, 150-250mg, 250-350mg and 350+mg respectively. Most self-reported doses range from 50 to 150mg or even up to 500mg. Furthermore, most users report repeated usage in order to extend their euphoric experience often leading to 0.5g to 2g of 3-MMC consumed in one sitting or even within a few hours. The drug lasts from 4-6 hours with its peak being 2-3 hours long. In a questionnaire-based study of self-reported 3-MMC users in Slovenia, it was found that 88.8% of users insufflated the drug while 42.6% took it orally. The study did not find any instances of users injecting 3-MMC. Moreover, 26% of the users reported taking more than 1.5 g of 3-mmc / 3mmc / buy 3-mmc online in a single sitting and over 50% reported having consuming more than 0.5g in a single sitting.

Adverse effects
The desired effects of 3-mmc / 3mmc / buy 3-mmc online are stimulation, spontaneous bodily sensations, euphoria, enhancement of empathy, affection and sociability, happiness, awareness and an increased appreciation of music which are similar effects of other amphetamines and drugs of abuse.The adverse effects can range from stuttering, fatigue, verbosity, reduced level of consciousness, depression, aggression, delirium and confusion, double vision, difficulty in concentration, headaches, dehydration, hallucinations, fear to more serious effects such as hypona-tremia, diaphoresis, seizures, hyperthermia and rhabdomyolysis.

Toxicity
Very few cases of overdoses have been recorded in literature for concentrations between 249 and 1600 ng/mL for 3-MMC. Since the concentration range is quite high in the literature, defining the concentration at which impairment or fatality occurs is very difficult. No correlation between the measured concentration and the type of intoxication was found. The most likely cause for this is the chemical instability of the drug. 3-mmc / 3mmc / buy 3-mmc online

Effects on animals
In animals, 3-MMC has a rather high absorption rate with the peak concentration being achieved within 5 to 10 minutes after oral ingestion and a plasma half-life of 0.8 hours. The bioavailability was tested to be around 7% and 3-MMC levels dropped below detectable levels after 24 hours of oral ingestion. Moreover, 3-mmc / 3mmc / buy 3-mmc online caused a significant change in the feeding behaviour of animals often resulting in weight gain over time. Caution is needed when applying the data for human safety from the extrapolated animal data because of low sample size, lack of data and low dosage.

Legal status
As of October 2015, 3-MMC is a controlled substance in China.

3-MMC is banned in the Czech Republic.

3-MMC was not banned by the United Nations Office on Drugs and Crime (UNODC) after a critical review.

3-MMC is currently not covered in the Dutch Opium Law and is therefore legal in the Netherlands. However, the Dutch government is going to add 3-mmc / 3mmc / buy 3-mmc online to the banned substance list in the 2nd half of 2021 (for it to be considered as illegal hard drug)

Additional information

Package

100g, 10g, 15g, 1kg, 250g, 25g, 500g, 50g

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